• 
  Rosario Central – River

  6 October

• 
  Boca Juniors – Newell`s

  5 October

• 
  Talleres – Belgrano

  5 October

• 
  Estudiantes LP – Barracas

  5 October

• 
  Godoy – Independiente

  5 October

• 
  Lanus – San Lorenzo

  5 October

• 
  Westerlo – Oud-Heverlee

  5 October

• 
  Brugge – Union

  5 October

• 
  Genk – Dender EH

  5 October

• 
  Anderlecht – Standard

  5 October

• 
  Cruzeiro-MG – Sport

  6 October

• 
  Ceara – Santos-SP

  6 October

• 
  Bahia – Flamengo-RJ

  5 October

• 
  Juventude – Fortaleza

  5 October

• 
  Sao Paolo – Palmeiras

  5 October

• 
  Vasco – Vitoria-BA

  5 October

• 
  Corinthians – Mirassol

  5 October

• 
  Boyaca Chico – Atletico

  6 October

• 
  Atletico Junior – Deportes

  5 October

• 
  Deportivo Pasto – Alianza

  5 October

• 
  Llaneros – Fortaleza

  5 October

• 
  Barcelona – Independiente

  5 October

• 
  Libertad – Orense

  5 October

• 
  Macara – Aucas

  5 October

• 
  Univ Catolica Quito – LDU

  5 October

• 
  Brentford – Manchester

  5 October

• 
  Aston Villa – Burnley

  5 October

• 
  Everton – Crystal Palace

  5 October

• 
  Newcastle United – Nottingham

  5 October

• 
  Wolverhampton – Brighton

  5 October

• 
  Lille – PSG

  5 October

• 
  Le Havre – Rennes

  5 October

• 
  Strasbourg – Angers

  5 October

• 
  AS Monaco – Nice

  5 October

• 
  Lyon – Toulouse

  5 October

• 
  Borussia M – Freiburg

  5 October

• 
  Hamburg – Mainz 05

  5 October

• 
  Stuttgart – Heidenheim

  5 October

• 
  Juventus – Milan

  5 October

• 
  Napoli – Genoa

  5 October

• 
  Bologna – Pisa

  5 October

• 
  Fiorentina – Roma

  5 October

• 
  Udinese – Cagliari

  5 October

• 
  Kashima Antlers – Gamba

  5 October

• 
  Dinamo Mn – Traktor

  6 October

• 
  Lokomotiv – SKA

  6 October

• 
  Avangard – Avtomobilist

  6 October

• 
  Torpedo NN – Dynamo Msk

  5 October

• 
  Ak Bars – Amur

  5 October

• 
  CSKA – Severstal

  5 October